The goal of this project is to explore the molecular mechanisms of cytotoxicity in natural killer (NK) cell and how to exploit the mechanics to potentially optimize cytotoxic cell therapies. This project arises from our ongoing work delineating how lytic granule positioning may impact the efficiency and effectiveness of NK cell killing and how we might intentionally control the mechanics of lytic granules.

Ph.D. in USA (Immunology)

• Collaborative, ambitious individuals with a strong interest in our research and environment
• Ability to work independently to develop research projects and mentor others
• Fearlessness in the design and implementation of new techniques and approaches to model human immune cell function
• Strong verbal and written communication skills
• Experience with human immune cells an asset
• Strong and advanced skills in quantitative live cell microscopy.

• CV
• Cover letter including a paragraph describing how your research interests fit with the job described
• Contact information for 3 references

• Email to: jso2121@cumc.columbia.edu

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Columbia University is one of the world's most important centers of research and at the same time a distinctive and distinguished learning environment for undergraduates and graduate students in many scholarly and professional fields. The University recognizes the importance of its location in New York City and seeks to link its research and teaching to the vast resources of a great metropolis. It seeks to attract a diverse and international faculty and student body, to support research and teaching on global issues, and to create academic relationships with many countries and regions. It expects all areas of the university to advance knowledge and learning at the highest level and to convey the products of its efforts to the world.

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