Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.
This position is full-time and works approximately 40 hours per week.
Department Name/Job Location:
This position is in the Department of Pediatric Rheumatology. This position is for the Medical School Campus.
This position will focus on genetic analysis of disorders of the immune system. Assists in developing and conducting research projects, including experimental design, data analysis, and documentation of experiment results.
PRIMARY DUTIES AND RESPONSIBILITIES:
Designs, develops, and implements:
Algorithms and computer software for analyzing high-throughput, massively parallel genomic data sets;
Relational databases to store disseminate and analyze data, including verification of data submitted and recommendations for analyses;
Web interfaces and queries to access relational databases; maintains web server;
Independent research projects, including design of research protocols and development of procedures for the collection, verification, and management of data.
Performs complex systems analysis of data and writes interpretative reports.
Evaluates commercial and academic bioinformatics software.
Trains other researchers on the everyday use of analysis software and research databases.
Assists with grant preparation and reporting of methods, data, and results.
Solves practical problems relating to difficulties with equipment or test subjects; suggests technical or procedural improvements in testing methods.
Bachelor’s degree in science or related field plus 4 years of experience required.
Master’s degree or Ph.D. in computer science or related field highly preferred.
Analytical, reasoning, and problem-solving skills.
Good understanding of computational biology, probabilistic models, statistics, machine learning, and discrete mathematics.
Ability to analyze and interpret large complex data sets, such as sequencing (Whole Exome Sequencing, Whole Genome Sequencing, RNA-seq), microarray gene expression studies, human genetic studies, and model organism studies, and to communicate data in a clear, concise manner
Expertise in standard bioinformatics tools.
Working knowledge of regulatory networks, hidden Markov models and profile methods, human genetics (SNP, etc.), and complex systems analysis.
Expertise in scientific programming languages (e.g., Python, R), scripting languages (e.g., PERL, BASH), database management software (MySQL, PostgreSQL) version control (GitHub, BitBucket, svn), virtualized/distributed computing (Docker, HPC, Cloud) and a UNIX/Linux environment.
Working knowledge of standard molecular biology techniques (PCR, qRT-PCR).
Expertise in molecular and functional genomic techniques is desired.
Basic experience or interest in immunologic disease is desired.
The hiring range for this position is $52,769 - $71,240 annually.
The Department of Pediatrics in collaboration with the McDonnell Genome Institute (MGI), a world leader in the fast-paced, constantly changing field of genomics, is seeking a highly-talented and motivated Bioinformaticist to analyze omics data using cutting-edge software tools and methods for genetic discovery in rare diseases. Working within the Department of Pediatrics in collaboration with the Bioinformatics & Genome Analytics group at MGI requires the innovative use of statistical models, machine learning and artificial intelligence to handle ever-increasing sequence data throughput. This position will focus on using genomic approaches to investigate mechanisms of rare pediatric immune-mediated diseases.�
This position is eligible for full-time benefits.� Please visit our website at http://hr.wustl.edu to view a summary of benefits.
Internal Applicant Instruction:
This position is grade R11.
Please attach a copy of your most current signed performance evaluation (completed within the last 18 months) to your online account. If you have not received a performance evaluation, you may provide two current signed letters of recommendation (written within the last 18 months), preferably to include one letter from either a current or recent former supervisor. To attach these documents, go to: My Career Tools, Add Attachment, Attachment Type – Performance Reviews or Letters of Recommendation.
Washington University in St. Louis, a medium-sized, independent university, is dedicated to challenging its faculty and students alike to seek new knowledge and greater understanding of an ever-changing, multicultural world. The University offers more than 90 programs and almost 1,500 courses leading to bachelor's, master's and doctoral degrees in a broad spectrum of traditional and interdisciplinary fields, with additional opportunities for minor concentrations and individualized programs. The faculty is composed of scholars, scientists, artists and members of the learned professions. They serve society by teaching; by adding to the store of human art, creativity, understanding, and wisdom; and by providing direct services, such as health care.